Machine learning matches enzymes with molecular substrates

2025. 10. 10. 14:37Science Reports & Study

 

RESEARCH BRIEFINGS

 

An approach that identifies, and predicts compatibility between, chemical and enzyme-sequence spaces can streamline and reduce risk in the discovery of enzymes that can catalyse a desired reaction. The strategy uses high-throughput experiments to generate data about enzyme-mediated reactions, and there is a tool that can predict compatible substrate–enzyme pairs.

https://www.nature.com/articles/d41586-025-03161-x