A map of mitochondrial biology reveals the energy landscape of the human brain
2025. 3. 31. 15:35ㆍScience Reports
Mapping the density, molecular features and energy-transformation capacity of cell organelles called mitochondria in the brain reveals region- and cell-type-specific variability that tracks with evolutionary patterns. Correlations between mitochondrial and brain-imaging metrics could enable future non-invasive explorations of mitochondrial bioenergetics in the brain in health and disease.
Mosharov, E.V., Rosenberg, A.M., Monzel, A.S. et al. A human brain map of mitochondrial respiratory capacity and diversity. Nature (2025).